Quantitative Analysis Methods for Paracetamol: A Comprehensive Overview

Authors

  • Himanshu Sharma Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)
  • Kaniz Fatma Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)
  • Zainab Khan Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)
  • Amodh Chaurasiya Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)
  • Devashree Jaiswal Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)
  • Garima Singh Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)
  • Kapil Kumar Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)
  • Shubhankit Soni Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)
  • Dr Alok Kumar Shukla Babu Sunder Singh College of Pharmacy, Raebareli Road, Nigohan, Lucknow - 226302 (U.P.)

DOI:

https://doi.org/10.62752/hhv8tg34

Keywords:

Quantitative analysis, pharmaceutical potency, Analytical techniques, Drug development

Abstract

Paracetamol, a widely used analgesic and antipyretic medication, requires rigorous quantitative analysis to ensure its safety, efficacy, and quality. This study aims to investigate and compare the active ingredient content of multiple Paracetamol brands using advanced analytical techniques such as High-Performance Liquid Chromatography (HPLC) and UV-Visible Spectrophotometry. The research methodology involves systematic sample collection, preparation, and analysis, followed by data interpretation and statistical analysis to identify significant differences between brands. Quality control measures are implemented to ensure the reliability and reproducibility of results. The findings hold significant implications for pharmaceutical quality assurance, regulatory compliance, and public health by assessing the consistency of active ingredient content across various Paracetamol brands. This study contributes valuable insights into the overall quality of these medications and addresses concerns regarding potential variations in drug content between manufacturers. The results may inform regulatory bodies, healthcare professionals, and consumers about the quality and reliability of different Paracetamol brands, potentially influencing prescribing practices, consumer choices, and regulatory oversight. The methodology employed serves as a model for similar investigations of other pharmaceutical products, contributing to the broader field of drug quality assessment and pharmacovigilance. 

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Published

2025-05-31

How to Cite

Quantitative Analysis Methods for Paracetamol: A Comprehensive Overview. (2025). International Journal of Pharmaceutical and Healthcare Innovation, 2(III), 571-581. https://doi.org/10.62752/hhv8tg34

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