The process of drug discovery and development consists of many stages.

Authors

  • Raj Kumar Singh Department of Pharmaceutical Chemistry, Institute of Pharmaceutical Sciences & Research (IPSR) Mahadev Campus, Soharamau, Unnao, Uttar Pradesh, 209859, India
  • Ramashish Maurya Department of Pharmaceutical Chemistry, Institute of Pharmaceutical Sciences & Research (IPSR) Mahadev Campus, Soharamau, Unnao, Uttar Pradesh, 209859, India
  • Adarsh kumar Department of Pharmaceutics, Institute of Pharmaceutical Sciences & Research (IPSR) Mahadev Campus, Soharamau, Unnao, Uttar Pradesh, 209859, India
  • Sulekha Bhardwaj Department of Pharmaceutics, K D C College of pharmacy, ole, Mathura, Uttar Pradesh 281122, India
  • Pankaj Singh Department of Pharmaceutics, K D C College of pharmacy, ole, Mathura, Uttar Pradesh 281122, India
  • Ram Pratap Verma Department of Pharmaceutical Chemistry, Institute of Pharmaceutical Sciences & Research (IPSR) Mahadev Campus, Soharamau, Unnao, Uttar Pradesh, 209859, India

DOI:

https://doi.org/10.62752/

Keywords:

Target validation, identification, lead optimization, preclinical trials, clinical trials, post-marketing surveillance, and new drug.

Abstract

The primary goal of the drug discovery process is to identify a chemical molecule that has therapeutic properties and has the potential to be used in the treatment and potential eradication of illnesses. The approach involves many stages: candidate identification, synthesis, characterization, validation, optimization, screening, and research to evaluate therapeutic efficacy. Once a chemical has shown its efficacy in this research, the process of drug development will begin prior to clinical trials. A treatment that satisfies all regulatory standards and is safe and effective has to undergo through multiple stages of the new drug development process. Our article's main thesis is that the procedure is so long away intricate, and costly that any new medication that is eventually approved for clinical usage must take into account a variety of biological targets, and it may be necessary to develop new research instruments in order to examine each new target. The journey from initial discovery to a marketable drug is a lengthy and arduous procedure. A substantial investment of about US $1 billion is required, and the process from discovery to obtaining an approved drug typically takes between 12 and 15 years. On average, one million compounds are screened, but only one is thoroughly explored at a later stage. The drug undergoes rigorous phase clinical trials before being made accessible to patients. This article provides a comprehensive description of the processes involved in the identification and creation of new pharmaceutical compounds..

 

Published

2024-05-18

Issue

Section

Articles

How to Cite

The process of drug discovery and development consists of many stages . (2024). International Journal of Pharmaceutical and Healthcare Innovation, 1(03), 174-184. https://doi.org/10.62752/

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