Recent developments in the search for anticancer drugs: A review

Abstract

Uncontrolled cell proliferation causes cancer, which is characterized by the growth of an unusually large tumor that first appears as a localized illness but has the potential to spread and affect other organs or critical functions. One of the most lethal diseases in modern history, cancer claims the lives of countless individuals annually. The efficacy of treatment for this condition has been impacted by socioeconomic circumstances, geographical differences in the disease, and the impact of easily accessible medical services. Finding new anticancer drugs has been a recent focus of research, and this study aimed to summaries previous articles on the subject. This review classifies a large number of findings into several categories, including anticancer therapeutic targets, chemical compounds with in vivo or in vitro cytotoxic drug discovery, breakthroughs derived from plants, and repurposing. Using PubMed Central, Google Scholar, and Science Direct, the previously published literature on anticancer drug discovery advancements from March 20 to May 12 was meticulously culled from publications. Items that I thought were relevant and up-to-date (2017–2023) were incorporated. This review summarizes recent advances in the hunt for anticancer medications by drawing on a variety of academic sources. This issue encompasses various aspects such as plant-derived cancer advancements, pharmaceuticals repurposed for cancer treatment, and prospective and clinically demonstrated pharmacological targets for anticancer drug binding. therapy, followed by a discussion of developments in innovative chemical compounds used in cancer therapy

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