Floating Microsphere: A Review on Novel Approach

Abstract

Microspheres that float around on the surface are also known as micro-balloons, floating microparticles, or hollow microspheres. Floating microspheres, according to strict definition, are spherical, centerless particles. Particles of diameters ranging from 1 to 1000 μm are these free-moving things. Floating microspheres are gaining a lot of interest because they have the potential to deliver drugs directly to the stomach. One type of non-effervescent drug delivery device that is gastrointestinal retained is the hollow microsphere, which is also called a floating microsphere. Hollow microspheres are spherical, coreless particles that are ideally between one and one thousand micrometers in size and composed of free-flowing powders of synthetic polymers or proteins. Medications that have an upper small intestine absorption window can benefit greatly from a controlled drug delivery system that has an extended stomach residence duration. Floating microspheres, sometimes called hollow microspheres, are gastro-retentive drug delivery devices that are based on the non-effervescent technique. Strictly speaking, hollow microspheres are spherical, coreless particles that are ideally between one and one thousand micrometers in size and formed of free-flowing powders of synthetic polymers or proteins. Floating microspheres that are able to retain their contents in the stomach for a long period are called gastro-retentive systems because of their low density and buoyancy. Fewer fluctuations in plasma drug concentration and increased stomach retention result from medicine administration at the prescribed pace. To make microspheres that float, scientists use evaporation and solvent diffusion.